Deciphering osteoconductive surface charge effects in sintered hydroxyapatite via piezoresponse force microscopy
نویسندگان
چکیده
Hydroxyapatite (HAp), a main constituent of the cortical bone, retains large surface charge that plays critical role in regeneration bones, whose source remains an enigma. Here, we used multi-eigenmode piezoresponse force microscopy via Pearson correlation and conducted multiscale material analysis to independently measure piezoelectric coefficient density HAp. Quantitative comparison was between measured conceptual values computed for all possible candidates charging such as piezoelectricity, chemically induced charging, flexoelectricity, defect dipole moment. The results presented Ca2+ ions released during local calcium orthophosphate phase transition at charging. Further showed ion concentration modulable using charged conductive tip, implying interstitial are mobile within HAp matrix. In this work, developed novel method effective arbitrary systems, thereby facilitating investigation biophysical phenomena related electromechanics. Most importantly, research promotes new understanding origin osteoconduction observed past works on
منابع مشابه
Vector piezoresponse force microscopy.
A novel approach for nanoscale imaging and characterization of the orientation dependence of electromechanical properties-vector piezoresponse force microscopy (Vector PFM)-is described. The relationship between local electromechanical response, polarization, piezoelectric constants, and crystallographic orientation is analyzed in detail. The image formation mechanism in vector PFM is discussed...
متن کاملElectrostatic-free piezoresponse force microscopy
Contact and non-contact based atomic force microscopy (AFM) approaches have been extensively utilized to explore various nanoscale surface properties. In most AFM-based measurements, a concurrent electrostatic effect between the AFM tip/cantilever and sample surface can occur. This electrostatic effect often hinders accurate measurements. Thus, it is very important to quantify as well as remove...
متن کاملContrast mechanism maps for piezoresponse force microscopy
Piezoresponse force microscopy (PFM) is one of the most established techniques for the observation and local modification of ferroelectric domain structures on the submicron level. Both electrostatic and electromechanical interactions contribute at the tip-surface junction in a complex manner, which has resulted in multiple controversies in the interpretation of PFM. Here we analyze the influen...
متن کاملBiological ferroelectricity uncovered in aortic walls by piezoresponse force microscopy.
Many biological tissues are piezoelectric and pyroelectric with spontaneous polarization. Ferroelectricity, however, has not been reported in soft biological tissues yet. Using piezoresponse force microscopy, we discover that the porcine aortic walls are not only piezoelectric, but also ferroelectric, with the piezoelectric coefficient in the order of 1 pm/V and coercive voltage approximately 1...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Applied Physics
سال: 2021
ISSN: ['1089-7550', '0021-8979', '1520-8850']
DOI: https://doi.org/10.1063/5.0028525